Metagenomic study of the viruses of African straw-coloured fruit bats: detection of a chiropteran poxvirus and isolation of a novel adenovirus.
Identifieur interne : 001900 ( Main/Exploration ); précédent : 001899; suivant : 001901Metagenomic study of the viruses of African straw-coloured fruit bats: detection of a chiropteran poxvirus and isolation of a novel adenovirus.
Auteurs : Kate S. Baker [Royaume-Uni] ; Richard M. Leggett ; Nicholas H. Bexfield ; Mark Alston ; Gordon Daly ; Shawn Todd ; Mary Tachedjian ; Clare E G. Holmes ; Sandra Crameri ; Lin-Fa Wang ; Jonathan L. Heeney ; Richard Suu-Ire ; Paul Kellam ; Andrew A. Cunningham ; James L N. Wood ; Mario Caccamo ; Pablo R. MurciaSource :
- Virology [ 1096-0341 ] ; 2013.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Virus.
- virologie : Chiroptera.
- Afrique, Analyse de regroupements, Analyse de séquence d'ADN, Animaux, Biodiversité, Données de séquences moléculaires, Métagénome, Phylogénie, Virus.
English descriptors
- KwdEn :
- MESH :
- geographic : Africa.
- classification : Viruses.
- genetics : Viruses.
- virology : Chiroptera.
- Animals, Biodiversity, Cluster Analysis, Metagenome, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA.
Abstract
Viral emergence as a result of zoonotic transmission constitutes a continuous public health threat. Emerging viruses such as SARS coronavirus, hantaviruses and henipaviruses have wildlife reservoirs. Characterising the viruses of candidate reservoir species in geographical hot spots for viral emergence is a sensible approach to develop tools to predict, prevent, or contain emergence events. Here, we explore the viruses of Eidolon helvum, an Old World fruit bat species widely distributed in Africa that lives in close proximity to humans. We identified a great abundance and diversity of novel herpes and papillomaviruses, described the isolation of a novel adenovirus, and detected, for the first time, sequences of a chiropteran poxvirus closely related with Molluscum contagiosum. In sum, E. helvum display a wide variety of mammalian viruses, some of them genetically similar to known human pathogens, highlighting the possibility of zoonotic transmission.
DOI: 10.1016/j.virol.2013.03.014
PubMed: 23562481
Affiliations:
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Emerging viruses such as SARS coronavirus, hantaviruses and henipaviruses have wildlife reservoirs. Characterising the viruses of candidate reservoir species in geographical hot spots for viral emergence is a sensible approach to develop tools to predict, prevent, or contain emergence events. Here, we explore the viruses of Eidolon helvum, an Old World fruit bat species widely distributed in Africa that lives in close proximity to humans. We identified a great abundance and diversity of novel herpes and papillomaviruses, described the isolation of a novel adenovirus, and detected, for the first time, sequences of a chiropteran poxvirus closely related with Molluscum contagiosum. In sum, E. helvum display a wide variety of mammalian viruses, some of them genetically similar to known human pathogens, highlighting the possibility of zoonotic transmission.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li></region><settlement><li>Cambridge</li></settlement><orgName><li>Université de Cambridge</li></orgName></list><tree><noCountry><name sortKey="Alston, Mark" sort="Alston, Mark" uniqKey="Alston M" first="Mark" last="Alston">Mark Alston</name><name sortKey="Bexfield, Nicholas H" sort="Bexfield, Nicholas H" uniqKey="Bexfield N" first="Nicholas H" last="Bexfield">Nicholas H. 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Holmes</name><name sortKey="Kellam, Paul" sort="Kellam, Paul" uniqKey="Kellam P" first="Paul" last="Kellam">Paul Kellam</name><name sortKey="Leggett, Richard M" sort="Leggett, Richard M" uniqKey="Leggett R" first="Richard M" last="Leggett">Richard M. Leggett</name><name sortKey="Murcia, Pablo R" sort="Murcia, Pablo R" uniqKey="Murcia P" first="Pablo R" last="Murcia">Pablo R. Murcia</name><name sortKey="Suu Ire, Richard" sort="Suu Ire, Richard" uniqKey="Suu Ire R" first="Richard" last="Suu-Ire">Richard Suu-Ire</name><name sortKey="Tachedjian, Mary" sort="Tachedjian, Mary" uniqKey="Tachedjian M" first="Mary" last="Tachedjian">Mary Tachedjian</name><name sortKey="Todd, Shawn" sort="Todd, Shawn" uniqKey="Todd S" first="Shawn" last="Todd">Shawn Todd</name><name sortKey="Wang, Lin Fa" sort="Wang, Lin Fa" uniqKey="Wang L" first="Lin-Fa" last="Wang">Lin-Fa Wang</name><name sortKey="Wood, James L N" sort="Wood, James L N" uniqKey="Wood J" first="James L N" last="Wood">James L N. Wood</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Baker, Kate S" sort="Baker, Kate S" uniqKey="Baker K" first="Kate S" last="Baker">Kate S. Baker</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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